1-甲基-2-(4-硝基苯基)苯合成路线 （共 27 条）
反应条件
1-((dimethylamino)(phenyl)methyl)naphthalen-2-ol; palladium diacetate; potassium carbonate in 1,4-dioxane; water T=40°C; Suzuki coupling; 5 h; Sonication;
参考文献
Chaudhary; Bedekar
Applied Organometallic Chemistry, 2012 , vol. 26, # 8 p. 430 - 437
反应条件
palladium diacetate; potassium carbonate in ethanol; N,N-dimethyl acetamide T=80°C; Suzuki coupling; 0.333333 h;
参考文献
Kong, Fanzhen; Zhou, Chunshan; Wang, Jinyun; Yu, Zhangyu; Wang, Ruihu
ChemPlusChem, 2013 , vol. 78, # 6 p. 536 - 545
反应条件
1: 4-nitro-aniline With tert.-butylnitrite; boron trifluoride diethyl etherate T=-15 - 5°C; 0.583333 h; 2: (2-methylphenyl)boronic acid With (R,R)-N,N'-(2-MeC6H4)2-N,N'-(cyclohexane-1,2-diyl)thiourea; palladium diacetate in methanol T=20°C; Suzuki reaction; 4 h;
参考文献
Dai, Mingji; Liang, Bo; Wang, Cuihua; Chen, Jiahua; Yang, Zhen
Organic Letters, 2004 , vol. 6, # 2 p. 221 - 224
反应条件
1: 2-methylphenylmagnesium chloride With zinc(II) chloride in tetrahydrofuran T=20°C; 0.333333 h; 2: 1-chloro-4-nitro-benzene With Pd0(tris(tert-butyl)phosphine)2 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=100°C; Negishi reaction; 2 h; Further stages.;
参考文献
Dai; Fu
Journal of the American Chemical Society, 2001 , vol. 123, # 12 p. 2719 - 2724
反应条件
KF in tetrahydrofuran
参考文献
Yale University
Patent: US6562989 B2, 2003 ;
反应条件
cesium fluoride; tri-cyclo-hexyl-phosphine; palladium diacetate in tetrahydrofuran T=55°C; Suzuki coupling; 17 h;
参考文献
Rostovtsev, Vsevolod V.; Bryman, Lois M.; Junk, Christopher P.; Harmer, Mark A.; Carcani, Liane G.
Journal of Organic Chemistry, 2008 , vol. 73, # 2 p. 711 - 714
反应条件
potassium fluoride; palladium in methanol Suzuki coupling reaction; 4 h; Heating;
参考文献
Kabalka; Namboodiri; Wang
Chemical Communications, 2001 , # 8 p. 775 - 775
反应条件
water; palladium diacetate; sodium carbonate T=80°C; Suzuki Coupling; 1 h; Green chemistry;
参考文献
Liu, Leifang; Dong, Yan; Tang, Nana
Green Chemistry, 2014 , vol. 16, # 4 p. 2185 - 2189
反应条件
tris(dibenzylideneacetone)dipalladium (0); [HP(t-Bu)3]BF4 in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=175°C; Negishi cross-coupling; 0.166667 h; microwave irradiation;
参考文献
Walla, Peter; Kappe, C. Oliver
Chemical Communications, 2004 , # 5 p. 564 - 565
反应条件
potassium fluoride; (1,2,3,4,5-pentaphenylferrocen-1'-yl)-di-tert-butylphosphine; palladium compound in toluene T=50°C; Suzuki coupling; 22 h;
参考文献
Kataoka, Noriyasu; Shelby, Quinetta; Stambuli, James P.; Hartwig, John F.
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5553 - 5566
