乙基6-(3-氯苯基)-6-氧代己酸酯合成路线 （共 3 条）
反应条件
N,N-dimethyl-formamide; palladium on activated charcoal in tetrahydrofuran; toluene T=25°C; Fukuyama coupling reaction; 22 h;
参考文献
Shimizu, Toshiaki; Seki, Masahiko
Tetrahedron Letters, 2001 , vol. 42, # 3 p. 429 - 432
反应条件
1: 5-Iodo-pentanoic acid ethyl ester With chloro-trimethyl-silane; ethylene dibromide; zinc in tetrahydrofuran T=55 - 60°C; 0.5 h; 2: m-Chlorthiobenzoesaeure-S-ethylester With 10percent Pd(OH)2/C in tetrahydrofuran; N,N-dimethyl-formamide; toluene T=25°C; Fukuyama coupling; 25 h; Further stages.;
参考文献
Mori, Yoshikazu; Seki, Masahiko
Journal of Organic Chemistry, 2003 , vol. 68, # 4 p. 1571 - 1574
反应条件
potassium hydroxide in ethanol; water; toluene
参考文献
American Cyanamid Company
Patent: US4536346 A1, 1985 ;
