2-氨基-6-氯吡嗪合成路线

参考文献

CANCER RESEARCH TECHNOLOGY LIMITED; COLLINS, Ian; LAINCHBURY, Michael; MATTHEWS, Thomas Peter; READER, John Charles
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6863-77-02-氨基吡嗪 4-氧化物

6863-73-62-氨基-3-氯吡嗪+

33332-29-52-氨基-5-氯吡嗪+

33332-28-42-氨基-6-氯吡嗪

参考文献

Journal of Chemical Research, Miniprint, , # 10 p. 2860 - 2875

544-97-8二甲基锌+

33332-28-42-氨基-6-氯吡嗪

5521-56-22-氨基-6-甲基吡嗪

参考文献

Walters, Iain A.S.
Tetrahedron Letters, 2006 , vol. 47, # 3 p. 341 - 344

33332-28-42-氨基-6-氯吡嗪+

5158-46-3甲基氯化锌

5521-56-22-氨基-6-甲基吡嗪

参考文献

Walters, Iain A.S.
Tetrahedron Letters, 2006 , vol. 47, # 3 p. 341 - 344

33332-28-42-氨基-6-氯吡嗪+

98-80-6苯硼酸

41270-69-36-苯基吡嗪-2-胺

参考文献

Djung, Jane F.; Mears, Richard. J.; Montalbetti, Christian A.G.N.; Coulter, Thomas S.; Golebiowski, Adam; Carr, Andrew N.; Barker, Oliver; Greis, Kenneth D.; Zhou, Songtao; Dolan, Elizabeth; Davis, Gregory F.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 8 p. 2742 - 2750

110-91-8吗啉+

33332-28-42-氨基-6-氯吡嗪

717847-03-56-(4-吗啉基)氨基吡嗪

参考文献

AMGEN INC.; DRANSFIELD, Paul John; GONZALEZ LOPEZ DE TURISO, Felix; PATTAROPONG, Vatee; SIMARD, Jillian L.
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WO 2012/003264 A1

67-56-1甲醇+

33332-28-42-氨基-6-氯吡嗪

6905-47-12-氨基-6-甲氧基吡嗪

参考文献

Kwak, Se Hun; Lee, Gee-Hyung; Gong, Young-Dae
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33332-28-42-氨基-6-氯吡嗪

6905-47-12-氨基-6-甲氧基吡嗪

参考文献

Glaxosmithkline LLC; Aubart, Kelly M.; Benowitz, Andrew B.; Fang, Yuhong; Hoffman, James; Karpinski, Joseph M.; Knox, Andrew Nicholson; Liao, Xiangmin; Qin, Donghui; Shi, Dongchuan; Spletstoser, Jared T.
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Location in patent: Page/Page column ;

107-20-0一氯乙醛+

33332-28-42-氨基-6-氯吡嗪

63744-41-25-氯咪唑并[1,2-a]吡嗪

参考文献

BRISTOL-MYERS SQUIBB COMPANY; AUSTIN, Joel, Francis; SHARMA, Lisa, S.; BALOG, James, Aaron; HUANG, Audris; VELAPARTHI, Upender; DARNE, Chetan, Padmakar; SAULNIER, Mark, George
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WO 2012/015723 A1

7252-83-72-溴-1,1-二甲氧基乙烷+

33332-28-42-氨基-6-氯吡嗪

63744-41-25-氯咪唑并[1,2-a]吡嗪

参考文献

NOVARTIS AG; BOCK, Mark G.; GAUL, Christoph; GUMMADI, Venkateshwar Rao; SENGUPTA, Saumitra
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WO 2010/149755 A1