1-二苯甲基-3-甲烷磺酸氮杂环丁烷合成路线 （共 34 条）
反应条件
in ethanol
T=50°C; 42 h;
参考文献
WAKUNAGA PHARMACEUTICAL CO., LTD.
Patent: EP1813610 A1, 2007 ;
Location in patent: Page/Page column 10 ;
反应条件
copper(I) bromide in tetrahydrofuran; diethyl ether
T=20 - 50°C; 17.5 h;
参考文献
Briner, Karin; Camp, Anne Marie; Cornell, Alan; Mazanetz, Michael Philip; Rothhaar, Roger Ryan; Victor, Frantz; Williams, Andrew Caerwyn; Zhang, Deyi
Patent: US2008/214520 A1, 2008 ;
Location in patent: Page/Page column 21 ;
反应条件
triethylamine in N,N-dimethyl-formamide
参考文献
Luzzio, Michael Joseph; Yang, Bingwei Vera; Marx, Matthew Arnold
Patent: US2002/42409 A1, 2002 ;
反应条件
in water; acetonitrile
T=100°C;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BUTTERWORTH, Sam; FINLAY, Maurice, Raymond, Verschoyle; WARD, Richard, Andrew; KADAMBAR, Vasantha, Krishna; CHANDRASHEKAR, Reddy, C.; MURUGAN, Andiappan; REDFEARN, Heather, Marie
Patent: WO2013/14448 A1, 2013 ;
Location in patent: Page/Page column 95 ;
WO 2013/014448 A1
