N1-(对甲苯)苯-1,4-二胺合成路线 （共 17 条）
反应条件
palladium in toluene
参考文献
Pfizer Inc.
Patent: US6492383 B1, 2002 ;
反应条件
ethanol; ammonium chloride; zinc
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
反应条件
1: water; calcium carbonate 2: hydrochloric acid 3: zinc; aqueous alcohol; ammonium chloride View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Jacobson
Justus Liebigs Annalen der Chemie, 1922 , vol. 427, p. 219
反应条件
1: sodium acetate / V methoxymethyl ester / 7 h / Inert atmosphere; Reflux 2: stannous chloride-dihydrate; ethanol / 1 h / 70 °C / Inert atmosphere View Scheme
参考文献
Li, Jie; Pei, Shuchen; Zhu, Yingxi; Wu, Jianbo; Chen, Yin; Zhang, Weiyu; Wu, Yong
Letters in Drug Design and Discovery, 2012 , vol. 9, # 4 p. 379 - 388
参考文献
Reichold
Justus Liebigs Annalen der Chemie, 1889 , vol. 255, p. 164
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Ullmann; Dahmen
Chemische Berichte, 1908 , vol. 41, p. 3746
反应条件
sulfuric acid Erwaermen des Reaktionsprodukts mit Natriumsulfid und wss.Natronlauge;
参考文献
I.G.Farbenind.
Patent: DE511526 , 1929 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 456
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Gen.Aniline Works
Patent: US1900426 , 1929 ;
反应条件
1: alcohol; diethyl ether; hydrochloric acid / man zerlegt das gefaellte Hydrochlorid durch alkoh. Ammoniak 2: alcoholic ammonium sulfide View Scheme
参考文献
Reichold
Justus Liebigs Annalen der Chemie, 1889 , vol. 255, p. 164
反应条件
1: alcohol; hydrochloric acid; water; sodium nitrite 2: alcohol; diethyl ether; hydrochloric acid / man zerlegt das gefaellte Hydrochlorid durch alkoh. Ammoniak 3: alcoholic ammonium sulfide View Scheme
参考文献
Reichold
Justus Liebigs Annalen der Chemie, 1889 , vol. 255, p. 164
