2-氨基-3-五氟苯基-丙酸合成路线 （共 5 条）
反应条件
1: Br2 / CCl4 2: (i) NaOEt, EtOH, (ii) /BRN= 647808/, DMF 3: aq. HCl View Scheme
参考文献
Filler,R. et al.
Journal of Organic Chemistry, 1969 , vol. 34, # 3 p. 534 - 538
参考文献
Filler,R. et al.
Journal of Organic Chemistry, 1969 , vol. 34, # 3 p. 534 - 538
反应条件
1: (i) NaOEt, EtOH, (ii) /BRN= 647808/, DMF 2: aq. HCl View Scheme
参考文献
Filler,R. et al.
Journal of Organic Chemistry, 1969 , vol. 34, # 3 p. 534 - 538
反应条件
1.) via its sodium salt, 2.) hydrolysis; Multistep reaction;
参考文献
Beguin, Claude; Hamman, Sylvain
Organic Magnetic Resonance, 1981 , vol. 16, # 2 p. 129 - 132
反应条件
1: 84 percent / NaHCO3 / acetone; H2O / 3 h / -10 - 25 °C 3: 6 N aq. HCl / 7 h / 70 - 80 °C View Scheme
参考文献
Soloshonok, V. A.; Shvyadas, V. K.; Kukhar, V. P.; Galaev, I. Yu.; Kozlova, E. V.; Svistunova, N. Yu.
Russian Journal of Bioorganic Chemistry, 1993 , vol. 19, # 4 p. 236 - 240
Bioorganicheskaya Khimiya, 1993 , vol. 19, # 4 p. 478 - 483
