3-溴-4H-噻吩并[3,2-b]吡咯-5-羧酸合成路线 (共 3 条)
反应条件
1: With potassium hydroxide; water in methanol T=85°C; 3 h; 2: With hydrogenchloride in methanol; water
参考文献
MERCK SHARP and DOHME LIMITED; MERCK and CO., INC.
Patent: WO2007/39773 A1, 2007 ;
Location in patent: Page/Page column 18 ;
反应条件
copper(l) chloride in N,N-dimethyl-formamide 16 h; Heating / reflux;
参考文献
MERCK SHARP and DOHME LIMITED; MERCK and CO., INC.
Patent: WO2007/39773 A1, 2007 ;
Location in patent: Page/Page column 19-20 ;