4-(1H-苯并咪唑-2-基)-1,2,5-恶二唑-3-胺合成路线 （共 3 条）
反应条件
hydroxylamine hydrochloride; potassium hydroxide in diethylene glycol dimethyl ether T=170°C; Cooling with ice;
参考文献
BASILEA PHARMACEUTICA AG; POHLMANN, Jens; BACHMANN, Felix
Patent: WO2011/12577 A1, 2011 ;
Location in patent: Page/Page column 29; 31 ;
反应条件
in ethanol 20 h; Heating;
参考文献
Sergievskii; Pirogov; Mel'nikova; Tselinskii
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 5 p. 717 - 720
反应条件
1: sodium nitrite; acetic acid / water / 20 °C / Cooling with ice 2: hydroxylamine hydrochloride; potassium hydroxide / diethylene glycol dimethyl ether / 170 °C / Cooling with ice View Scheme
参考文献
BASILEA PHARMACEUTICA AG; POHLMANN, Jens; BACHMANN, Felix
Patent: WO2011/12577 A1, 2011 ;
