(R)-Dragonfly N-Trifluoroacetamide合成路线 （共 8 条）
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in 1,4-dioxane 24 h; Heating;
参考文献
Chambers; Kurrasch-Orbaugh; Parker; Nichols
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 1003 - 1010
反应条件
1: oxalyl chloride; pyridine / CH2Cl2 / 3.5 h / 0 - 20 °C 2: AlCl3 / CH2Cl2 / 16 h 3: 92 percent / TFA; Et3SiH / 6 h / Heating 4: 64 percent / DDQ / dioxane / 24 h / Heating View Scheme
参考文献
Chambers; Kurrasch-Orbaugh; Parker; Nichols
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 1003 - 1010
反应条件
1: 91 percent / Br2; ZnCl2 / acetic acid 2: 79 percent / Mg; EtMgBr / tetrahydrofuran / 3 h / Heating 3: AlCl3 / CH2Cl2 / 16 h 4: 92 percent / TFA; Et3SiH / 6 h / Heating 5: 64 percent / DDQ / dioxane / 24 h / Heating View Scheme
参考文献
Chambers; Kurrasch-Orbaugh; Parker; Nichols
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 1003 - 1010
反应条件
1: 88 percent / SOCl2; pyridine / 20 °C 2: 91 percent / Br2; ZnCl2 / acetic acid 3: 79 percent / Mg; EtMgBr / tetrahydrofuran / 3 h / Heating 4: AlCl3 / CH2Cl2 / 16 h 5: 92 percent / TFA; Et3SiH / 6 h / Heating 6: 64 percent / DDQ / dioxane / 24 h / Heating View Scheme
参考文献
Chambers; Kurrasch-Orbaugh; Parker; Nichols
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 1003 - 1010
反应条件
1: AlCl3 / CH2Cl2 / 16 h 2: 92 percent / TFA; Et3SiH / 6 h / Heating 3: 64 percent / DDQ / dioxane / 24 h / Heating View Scheme
参考文献
Chambers; Kurrasch-Orbaugh; Parker; Nichols
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 1003 - 1010
反应条件
1: 79 percent / Mg; EtMgBr / tetrahydrofuran / 3 h / Heating 2: AlCl3 / CH2Cl2 / 16 h 3: 92 percent / TFA; Et3SiH / 6 h / Heating 4: 64 percent / DDQ / dioxane / 24 h / Heating View Scheme
参考文献
Chambers; Kurrasch-Orbaugh; Parker; Nichols
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 1003 - 1010
反应条件
1: AlCl3 / CH2Cl2 / 16 h 2: 92 percent / TFA; Et3SiH / 6 h / Heating 3: 64 percent / DDQ / dioxane / 24 h / Heating View Scheme
参考文献
Chambers; Kurrasch-Orbaugh; Parker; Nichols
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 1003 - 1010
反应条件
1: 92 percent / TFA; Et3SiH / 6 h / Heating 2: 64 percent / DDQ / dioxane / 24 h / Heating View Scheme
参考文献
Chambers; Kurrasch-Orbaugh; Parker; Nichols
Journal of Medicinal Chemistry, 2001 , vol. 44, # 6 p. 1003 - 1010
