N-去(4-磺酰氨基苯基)-N'-(4-磺酰氨基苯基)塞来考昔合成路线 （共 2 条）
反应条件
1: 4-sulfonamide-phenyl boronic acid With di-tert-butylazodicarboxylate; copper (II) acetate monohydrate in methanol T=65°C; 1 h; 2: 1,1,1-trifluoro-4-(4`-methylphenyl)-2,4-butanedione With hydrogenchloride in 1,4-dioxane; methanol T=20 - 80°C;
参考文献
Beveridge, Ramsay E.; Fernando, Dilinie; Gerstenberger, Brian S.
Tetrahedron Letters, 2010 , vol. 51, # 38 p. 5005 - 5008
反应条件
in water; ethyl acetate 2 h; RefluxLarge scale reaction; regioselective reaction;
参考文献
Reddy, Anumula Raghupathi; Sampath, Alla; Goverdhan, Gilla; Yakambaram, Bojja; Mukkanti, Kagga; Reddy, Padi Pratap
Organic Process Research and Development, 2009 , vol. 13, # 1 p. 98 - 101
