2-二甲基氨基-1-苯乙酮合成路线 （共 24 条）
反应条件
1: With trifluorormethanesulfonic acid in dichloromethane T=60 - 80°C; Houben-Housch synthesis; Inert atmosphere; 2: With water in dichloromethane Houben-Housch synthesis; Inert atmosphereCooling with ice; 3: With sodium hydroxide in water Inert atmosphere;
参考文献
Raja, Erum K.; Klumpp, Douglas A.
Tetrahedron, 2011 , vol. 67, # 25 p. 4494 - 4497
反应条件
potassium carbonate in acetonitrile T=20°C; Inert atmosphere;
参考文献
Soheili, Arash; Tambar, Uttam K.
Journal of the American Chemical Society, 2011 , vol. 133, # 33 p. 12956 - 12959
反应条件
sodium in dimethyl sulfoxide T=30 - 35°C; further solvents, temperatures and base; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kocharyan, S. T.; Razina, T. L.; Ogandzhanyan, S. M.; Babayan, A. T.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, p. 1256 - 1260
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 7 p. 1413 - 1417
反应条件
methanol T=150 - 170°C;
参考文献
Iwao et al.
Yakugaku Zasshi, 1954 , vol. 74, p. 551,553
Chem.Abstr., 1955 , p. 8175
参考文献
Sadet; Lipszyc; Chenu; et al.
European Journal of Medicinal Chemistry, 1978 , vol. 13, # 3 p. 277 - 288
参考文献
Eidebenz
Archiv der Pharmazie (Weinheim, Germany), 1942 , vol. 280, p. 49,61
参考文献
Chem. Werke Albert
Patent: DE681849 , 1936 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 25, p. 343
Full Text Show Details
Chem. Werke Albert
Patent: DE651543 , 1936 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 24, p. 364
参考文献
Jemison, Robert W.; Mageswaran, Sivapathasuntharam; Ollis, W. David; Sutherland, Ian O.; Thebtaranonth, Yodhathai
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1154 - 1164
反应条件
in methanol 114 h; 6 kbar;
参考文献
Matsumoto, Kiyoshi; Hashimoto, Shiro; Otani, Shinichi; Amita, Fujitsugu; Osugi, Jiro
Synthetic Communications, 1984 , vol. 14, # 6 p. 585 - 590
反应条件
1: 45 percent / CH2Cl2 2: 130 mg / 2 h / 53 °C View Scheme
参考文献
Jemison, Robert W.; Mageswaran, Sivapathasuntharam; Ollis, W. David; Sutherland, Ian O.; Thebtaranonth, Yodhathai
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1154 - 1164
