醋酸(E)-11-十四烯酯合成路线 （共 62 条）
反应条件
1: 93 percent / DIBAH / diethyl ether; toluene / 1.5 h / -20 °C 2: 97 percent / pyridine / 18 h / -5 - 0 °C 3: 82 percent / LiAlH4 / diethyl ether / 1.5 h 4: 1.) DIBAH, ZrCl4, 2.) O2 / 1.) toluene, hexane, 7 h, 2.) toluene, hexane, from 0 to 60 deg C, 5 h 5: 92 percent / pyridine / 24 h / Ambient temperature View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Vakhidov, R. R.; Berg, A. A.; Muslukhov, R. R.; Tolstikov, G. A.
Chemistry of Natural Compounds, 1992 , vol. 28, # 2 p. 237 - 240
Khimiya Prirodnykh Soedinenii, 1992 , # 2 p. 272 - 276
反应条件
1: 82 percent / LiAlH4 / diethyl ether / 1.5 h 2: 1.) DIBAH, ZrCl4, 2.) O2 / 1.) toluene, hexane, 7 h, 2.) toluene, hexane, from 0 to 60 deg C, 5 h 3: 92 percent / pyridine / 24 h / Ambient temperature View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Vakhidov, R. R.; Berg, A. A.; Muslukhov, R. R.; Tolstikov, G. A.
Chemistry of Natural Compounds, 1992 , vol. 28, # 2 p. 237 - 240
Khimiya Prirodnykh Soedinenii, 1992 , # 2 p. 272 - 276
反应条件
1: LiAlH4 / diethyl ether / 1 h / 0 °C 2: p-toluenesulfonic acid / methanol; H2O / 3 h / Heating 3: 83 percent / pyridine / 1 h / Heating View Scheme
参考文献
Canevet; Roeder; Vostrowsky; Bestmann
Chemische Berichte, 1980 , vol. 113, # 3 p. 1115 - 1120
反应条件
1: 90 percent / H2SO4 / 24 h / Heating 2: 70 percent / PCC, NaOAc / CH2Cl2 / 24 h / Ambient temperature 3: n-BuLi / toluene / 2 h / 25 °C 4: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating 5: pyridine / 24 h / 25 °C View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
1: 92 percent / 2N NaOH / 5 h / Heating 2: 90 percent / H2SO4 / 24 h / Heating 3: 70 percent / PCC, NaOAc / CH2Cl2 / 24 h / Ambient temperature 4: n-BuLi / toluene / 2 h / 25 °C 5: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating 6: pyridine / 24 h / 25 °C View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
1: 70 percent / PCC, NaOAc / CH2Cl2 / 24 h / Ambient temperature 2: n-BuLi / toluene / 2 h / 25 °C 3: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating 4: pyridine / 24 h / 25 °C View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
1: n-BuLi / toluene / 2 h / 25 °C 2: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating 3: pyridine / 24 h / 25 °C View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
1: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating 2: pyridine / 24 h / 25 °C View Scheme
参考文献
Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos; Szantay, Csaba
Acta Chimica Hungarica, 1988 , vol. 125, # 6 p. 797 - 820
反应条件
1.1: magnesium / tetrahydrofuran 1.2: 9 h / 2 - 20 °C / Inert atmosphere 2.1: methanol; toluene-4-sulfonic acid / 24 h / 20 °C 3.1: pyridine / 24 h / 20 °C View Scheme
参考文献
Shakhmaev; Ishbaeva; Shayakhmetova
Russian Journal of General Chemistry, 2009 , vol. 79, # 6 p. 1171 - 1174
反应条件
1.1: bromine; triphenylphosphine / chloroform / 3 h / 20 °C / Inert atmosphere 2.1: magnesium / tetrahydrofuran 2.2: 9 h / 2 - 20 °C / Inert atmosphere 3.1: methanol; toluene-4-sulfonic acid / 24 h / 20 °C 4.1: pyridine / 24 h / 20 °C View Scheme
参考文献
Shakhmaev; Ishbaeva; Shayakhmetova
Russian Journal of General Chemistry, 2009 , vol. 79, # 6 p. 1171 - 1174
