1: With phosphorus pentachloride; trichlorophosphate T=110 - 120°C; Heating / reflux; 2: With sodium hydrogencarbonate in dichloromethane; water

1: 1-methyl-pyrrolidin-2-one / 80 - 150 °C / Inert atmosphere 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 24 h / 20 °C 3: N,N-diethylaniline; trichlorophosphate / 4 h / Inert atmosphere; Reflux View Scheme

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 24 h / 20 °C 2: N,N-diethylaniline; trichlorophosphate / 4 h / Inert atmosphere; Reflux View Scheme

ammonia in dichloromethane T=20°C;