8-溴喹唑啉-2,4(1h,3h)-二酮合成路线 （共 3 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=20°C; 24 h;
参考文献
Hernandez, Armando R.; Kool, Eric T.
Organic Letters, 2011 , vol. 13, # 4 p. 676 - 679
反应条件
1: 1-methyl-pyrrolidin-2-one / 80 - 150 °C / Inert atmosphere 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 24 h / 20 °C View Scheme
参考文献
Organic Letters, , vol. 13, # 4 p. 676 - 679
反应条件
1: With phosphorus pentachloride; trichlorophosphate T=110 - 120°C; Heating / reflux; 2: With sodium hydrogencarbonate in dichloromethane; water
参考文献
PFIZER PRODUCTS INC.
Patent: WO2007/125405 A2, 2007 ;
Location in patent: Page/Page column 25; 81 ;
WO 2007/125405 A2
