2-(2-硝基苯基)乙胺合成路线 （共 16 条）
反应条件
1: With triphenylphosphine; calcium carbonate in benzene T=20°C; 2: With hydrogen bromide in water; acetic acid T=100°C; 1 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/99268 A2, 2006 ;
Location in patent: Page/Page column 59 ;
WO 2006/099268 A2
反应条件
(i) aq. NaN3, DMSO, (ii) Ph3P, benzene, (iii) aq. HBr, AcOH; Multistep reaction;
参考文献
Gutierrez, Corey; Termin, Andreas; Hadida-Ruah, Sara; Joshi, Pramod; Bergeron, Daniele; Yoo, Sanghee; Binch, Hayley; Come, Jon; Cao, Jingrong; Nanthakumar, Suganthi
Patent: US2008/4261 A1, 2008 ;
Location in patent: Page/Page column 139 ;
US 20080004261 A1
反应条件
borane in 1,4-dioxane
参考文献
Frontana-Uribe; Moinet; Toupet
European Journal of Organic Chemistry, 1999 , # 2 p. 419 - 430
反应条件
hydrogen azide; chloroform; sulfuric acid
参考文献
Kornblum; Iffland
Journal of the American Chemical Society, 1949 , vol. 71, p. 2137,2138,2140
反应条件
4-(N,N-dimethlyamino)pyridine; trifluoromethylsulfonic anhydride; ammonia 1.) CH2Cl2, from -30 deg C to RT, 2.) THF, from -30 deg C to RT; Multistep reaction;
参考文献
Muchowski,J.M.
Canadian Journal of Chemistry, 1971 , vol. 49, p. 2023 - 2028
参考文献
Johnson; Guest
American Chemical Journal, 1910 , vol. 43, p. 322
反应条件
sulfuric acid; nitric acid
参考文献
Ehrlich; Pistschimuka
Chemische Berichte, 1912 , vol. 45, p. 2430
Full Text Show Details
Goss; Hanhart; Ingold
Journal of the Chemical Society, 1927 , p. 260
反应条件
1: nitric acid / 0 °C 2: hydrobromic acid View Scheme
参考文献
Johnson; Guest
American Chemical Journal, 1910 , vol. 43, p. 322
反应条件
1: 210 - 220 °C / durch Erhitzen zuletzt auf 290grad 2: nitric acid / 0 °C 3: hydrobromic acid View Scheme
参考文献
Johnson; Guest
American Chemical Journal, 1910 , vol. 43, p. 322
反应条件
1: NaBH4, AlCl3 2: aq. HBr 3: (i) aq. NaN3, DMSO, (ii) Ph3P, benzene, (iii) aq. HBr, AcOH View Scheme
参考文献
Muchowski,J.M.
Canadian Journal of Chemistry, 1971 , vol. 49, p. 2023 - 2028
