4-((N-boc-氨基)甲基)苯硼酸频那醇酯合成路线 （共 5 条）
反应条件
triethylamine in dichloromethane T=20°C; 2 h;
参考文献
JANSSEN PHARMACEUTICA N.V.; ADDEX PHARMACEUTICALS S.A.
Patent: WO2007/104783 A2, 2007 ;
Location in patent: Page/Page column 53 ;
WO 2007/104783 A2
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in N,N-dimethyl-formamide T=80°C; 12 h; Inert atmosphere;
参考文献
Howgego, Joshua D.; Butts, Craig P.; Crump, Matthew P.; Davis, Anthony P.
Chemical Communications, 2013 , vol. 49, # 30 p. 3110 - 3112
反应条件
potassium acetate in tetrahydrofuran; n-heptane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide
参考文献
Hirst, Gavin C.; Calderwood, David; Munschauer, Rainer; Arnold, Lee D.; Johnston, David N.; Rafferty, Paul
Patent: US2003/153752 A1, 2003 ;
反应条件
1: toluene / 2 h / 30 °C 2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran / 24 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 33 p. 8666 - 8670
Angew. Chem., , vol. 125, # 33 p. 8828 - 8832,5
反应条件
1: toluene / 2 h / 30 °C 2: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran / 24 h / |Inert atmosphere; |Reflux View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 33 p. 8666 - 8670
Angew. Chem., , vol. 125, # 33 p. 8828 - 8832,5
