(4-羟基苯基)-吡啶-2-基甲酮合成路线 （共 6 条）
反应条件
1: With boron tribromide in dichloromethane T=-78 - 20°C; 2: With sodium hydrogencarbonate in dichloromethane
参考文献
AMGEN INC.
Patent: US2010/160280 A1, 2010 ;
Location in patent: Page/Page column 79 ;
反应条件
aluminium trichloride T=160°C; 4 h;
参考文献
Mereyala, Hari Babu; Sambaru, Kalyani
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 3 p. 615 - 617
反应条件
1: 8.4 g / triethylamine / CH2Cl2 / 0 - 20 °C 2: 56 percent / AlCl3 / 4 h / 160 °C View Scheme
参考文献
Mereyala, Hari Babu; Sambaru, Kalyani
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 3 p. 615 - 617
反应条件
1: thionyl chloride / benzene / 12 h / Heating 2: 8.4 g / triethylamine / CH2Cl2 / 0 - 20 °C 3: 56 percent / AlCl3 / 4 h / 160 °C View Scheme
参考文献
Mereyala, Hari Babu; Sambaru, Kalyani
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 3 p. 615 - 617
反应条件
1: 94.5 percent / sodium borohydride / methanol / 2 h / 0 - 20 °C 2: 69 percent / H3PO4 / H2O / 0.5 h / 100 °C 3: 88 percent / pyridine / CH2Cl2 / 2 h / 0 - 20 °C View Scheme
参考文献
Mereyala, Hari Babu; Sambaru, Kalyani
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 3 p. 615 - 617
反应条件
1: 94.5 percent / sodium borohydride / methanol / 2 h / 0 - 20 °C 2: 69 percent / H3PO4 / H2O / 0.5 h / 100 °C View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 44, # 3 p. 615 - 617
