苄氧羰基-L-脯氨酸 4-硝基苯基酯合成路线 （共 14 条）
反应条件
n-ethyl morpholine; hexamethylphosphorous triamide dichloride in dichloromethane 1) 0 deg C, 2 h, 2) overnight, r.t.;
参考文献
Appel, Rolf; Glaesel, Ursula
Chemische Berichte, 1980 , vol. 113, # 11 p. 3511 - 3516
反应条件
triethylamine in ethyl acetate
反应条件
1: aq. NaOH 2: dicyclohexylcarbodiimide View Scheme
参考文献
Journal of the American Chemical Society, , vol. 120, # 39 p. 10194 - 10198
反应条件
1: aq. NaOH 2: dicyclohexylcarbodiimide View Scheme
参考文献
Journal of the American Chemical Society, , vol. 120, # 39 p. 10194 - 10198
参考文献
Journal of the American Chemical Society, , vol. 81, p. 3980,3982
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine 1.) CH2Cl2, 0 deg C, 10 min, 2.) 0 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 50, # 5 p. 560 - 565
反应条件
ammonia; triethylamine in methanol T=0°C; Reflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 44, # 7 p. 2807 - 2814
反应条件
in N,N-dimethyl-formamide T=30°C; Rate constant;
参考文献
Wante, Dirk P. M.; Anteunis, Marc J. O.
Bulletin des Societes Chimiques Belges, 1984 , vol. 93, # 1 p. 73 - 82
反应条件
1: 1) Ammonia, 2) 1,2,4-triazole / 1) Chloroform, 10 min, room temperature, 2) ethyl acetate, 1 h, room temperature. 2: 94 percent / Ammonia / methanol / 24 h / Ambient temperature View Scheme
参考文献
Nikolaev, S. V.; Martinov, V. F.
Chemistry of Natural Compounds, 1985 , vol. 21, # 2 p. 269 - 270
Khimiya Prirodnykh Soedinenii, 1985 , # 2 p. 281 - 282
反应条件
1: 42 percent / 1.0N NaOH / dioxane / 24 h / Ambient temperature
2: H2 / Pd-C / aq. NaOH
View Scheme
参考文献
Anokhina, V. V.; Sorochinskaya, E. I.; Golubovich, V. P.; Kinarskii, L. I.; Martynov, V. F.
J. Gen. Chem. USSR (Engl. Transl.), 1990 , vol. 60, # 1.2 p. 203 - 211,178 - 184
