Boc-beta-丙氨酸合成路线 (共 48 条)
反应条件
sodium hydroxide in water; tert-butyl alcohol T=20°C;
参考文献
Sinha, Manish; Dola, Vasanth R.; Agarwal, Pooja; Srivastava, Kumkum; Haq, Wahajul; Puri, Sunil K.; Katti, Seturam B.
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 14 p. 3573 - 3586
反应条件
1: With potassium permanganate; sodium hydroxide in water T=20°C; 7 h; 2: With potassium hydrogensulfate in water
参考文献
Weitman, Michal; Lerman, Keti; Nudelman, Abraham; Major, Dan Thomas; Hizi, Amnon; Herschhorn, Alon
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 2 p. 447 - 467
反应条件
triethylamine in 1,4-dioxane; water T=20°C; 3 h;
参考文献
Lippard, Stephen J.; Barnes, Carmen M.; Haskel, Ariel; Barnes, Katie R.
Patent: US2004/235712 A1, 2004 ;
Location in patent: Page/Page column 34 ;
反应条件
lithium hydroxide; dihydrogen peroxide in tetrahydrofuran T=0°C; 0.333333 h;
参考文献
Journal of Organic Chemistry, , vol. 66, # 23 p. 7832 - 7840
反应条件
sodium hydroxide in tetrahydrofuran; dichloromethane; water
反应条件
triethylamine in water; acetone 5 h; Ambient temperature;
参考文献
Marchand-Brynaert, Jacqueline; Bounkhala-Khrouz, Zoubida; Vanlierde, Huguette; Ghosez, Leon
Heterocycles, 1990 , vol. 30, # 2 p. 971 - 982
反应条件
in tert-butyl alcohol
参考文献
G. D. Searle and Co.
Patent: US5182272 A1, 1993 ;
反应条件
1: Et3N / dioxane 2: KOCl / dioxane; H2O View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 5 p. 1274 - 1279
反应条件
KOCl in 1,4-dioxane; water
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 5 p. 1274 - 1279
反应条件
triethylamine in chloroform; N,N-dimethyl-formamide
参考文献
Chemical and pharmaceutical bulletin, , vol. 15, # 12 p. 2015 - 2016