3-(三氟甲基)苯氧基苯; 3-(三氟甲基)二苯醚合成路线 （共 15 条）
反应条件
[Ni0(1,5-cyclooctadiene)2]; caesium carbonate; dcype in anhydrous xylene T=160°C; 72 h;
参考文献
Wang, Jiayi; Ferguson, Devin M.; Kalyani, Dipannita
Tetrahedron, 2013 , vol. 69, # 27-28 p. 5780 - 5790
反应条件
1: phenol With potassium tert-butylate in tetrahydrofuran T=0°C; 0.25 h; 2: bis(3-trifluoromethylphenyl)iodonium tetrafluoroborate in tetrahydrofuran T=40°C; 0.25 h;
参考文献
Jalalian, Nazli; Petersen, Tue B.; Olofsson, Berit
Chemistry--A European Journal, 2012 , vol. 18, # 44 p. 14140 - 14149,10
反应条件
1: 3-trifluoromethyl-phenol With potassium tert-butylate in tetrahydrofuran T=0°C; 0.25 h; 2: Diphenyliodonium triflate in tetrahydrofuran T=40°C; 0.5 h;
参考文献
Jalalian, Nazli; Petersen, Tue B.; Olofsson, Berit
Chemistry--A European Journal, 2012 , vol. 18, # 44 p. 14140 - 14149,10
反应条件
sodium hydroxide in water T=20 - 60°C; 5 h;
参考文献
Lindstedt, Erik; Ghosh, Raju; Olofsson, Berit
Organic Letters, 2013 , vol. 15, # 23 p. 6070 - 6073
反应条件
aluminum oxide; potassium fluoride; copper(l) iodide; 1,10-phenanthroline T=110°C; 11 h;
参考文献
Hosseinzadeh, Rahman; Tajbakhsh, Mahmood; Mohadjerani, Maryam; Alikarami, Mohammad
Synlett, 2005 , # 7 art. no. D28904ST, p. 1101 - 1104
反应条件
pyridine; copper; potassium carbonate; potassium iodide T=150°C; 20 h;
参考文献
Murakami; Watanabe; Hagiwara; Akiyama; Ishii
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 8 p. 1281 - 1286
反应条件
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0.17 h / 20 °C 2.1: potassium tert-butylate / tetrahydrofuran / 0.25 h / 0 °C 2.2: 0.5 h / 40 °C View Scheme
参考文献
Jalalian, Nazli; Petersen, Tue B.; Olofsson, Berit
Chemistry--A European Journal, 2012 , vol. 18, # 44 p. 14140 - 14149,10
反应条件
1.1: boron trifluoride diethyl etherate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 20 °C 1.2: 0.5 h / 20 °C 2.1: potassium tert-butylate / tetrahydrofuran / 0.25 h / 0 °C 2.2: 0.25 h / 40 °C View Scheme
参考文献
Jalalian, Nazli; Petersen, Tue B.; Olofsson, Berit
Chemistry--A European Journal, 2012 , vol. 18, # 44 p. 14140 - 14149,10
反应条件
hydrogen; palladium on activated charcoal in ethanol; acetic acid
参考文献
Matthews, Donald P.; Whitten, Jeffrey P.; McCarthy, James R.
Tetrahedron Letters, 1986 , vol. 27, # 40 p. 4861 - 4864
反应条件
1: ZnCl2 2: 1.) 1,3-dibromo-5,5-dimethylhydantoin (DBH); 2.) HF/pyridine / 1.) CH2Cl2, -20 deg C to -30 deg C, 3h; 2.) -30 deg C to RT, 1h 3: H2 (50 psi) / 10percent Pd/C / ethanol; acetic acid View Scheme
参考文献
Matthews, Donald P.; Whitten, Jeffrey P.; McCarthy, James R.
Tetrahedron Letters, 1986 , vol. 27, # 40 p. 4861 - 4864
