(S)-beta-[[(苯基甲氧基)羰基]氨基]-苯丙酸甲酯合成路线 （共 3 条）
反应条件
sodium hydroxide in methanol; isopropyl alcohol T=20°C; 2 h; Inert atmosphereLarge scale;
参考文献
Haycock-Lewandowski, Sarah J.; Wilder, Alexander; Ahman, Jens
Organic Process Research and Development, 2008 , vol. 12, # 6 p. 1094 - 1103
反应条件
1: sodium hydroxide / methanol; isopropyl alcohol / 2 h / 20 °C / |Inert atmosphere; |Large scale 2: boron trifluoride / tetrahydrofuran / 3 h / 0 - 10 °C / |Inert atmosphere; |Large scale View Scheme
参考文献
Haycock-Lewandowski, Sarah J.; Wilder, Alexander; Ahman, Jens
Organic Process Research and Development, 2008 , vol. 12, # 6 p. 1094 - 1103
反应条件
1: 77 percent / H2, conc. HCl / 10percent Pd/C / methanol / 3.5 h / 760 Torr / Ambient temperature 2: 74 percent / 10percent aq. NaOH / 3 h View Scheme
参考文献
Crombie, Leslie; Haigh, David; Jones, Raymond C. F.; Mat-Zin, Ab. Rasid
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2047 - 2054
