5-甲基噁唑-4-羧酸乙酯合成路线 （共 4 条）
反应条件
potassium tert-butylate in tetrahydrofuran T=0 - 20°C; Inert atmosphere;
参考文献
Theveau, Laure; Verrier, Cecile; Lassalas, Pierrik; Martin, Thibaut; Dupas, Georges; Querolle, Olivier; Van Hijfte, Luc; Marsais, Francis; Hoarau, Christophe
Chemistry - A European Journal, 2011 , vol. 17, # 51 p. 14450 - 14463
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=80°C; 6 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 22, p. 283 - 292
反应条件
hydrogenchloride T=100°C; 6 h;
参考文献
Armarego, Wilfred L. F.; Taguchi, Hiroyasu; Cotton, Richard G. H.; Battiston, Sandra; Leong, Lillian
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 283 - 292
反应条件
diisobutylaluminium hydride
T=-78 - 20°C; 12.0833 h;
参考文献
AVEXA LIMITED
Patent: WO2007/124546 A1, 2007 ;
Location in patent: Page/Page column 60 ;
