N-乙酰-2'-脱氧-胞苷合成路线 (共 11 条)
反应条件
1: acetic acid With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-[1,3,5]triazine in dichloromethane T=20°C; 2: [14C]-Deoxycytidine in dichloromethane; N,N-dimethyl-formamide T=20 - 50°C;
参考文献
Rode, Ambadas B.; Son, Sang Jun; Hong, In Seok
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 7 p. 2061 - 2064
反应条件
in N,N-dimethyl-formamide T=20°C; 2 h;
参考文献
Reid, Andrew K.; McHugh, Callum J.; Richie, Graham; Graham, Duncan
Tetrahedron Letters, 2006 , vol. 47, # 25 p. 4201 - 4203
反应条件
in N,N-dimethyl-formamide
参考文献
Reddy; Hanna, Naeem B.; Farooqui, Firdous
Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1589 - 1598
反应条件
sodium hydroxide in 1,4-dioxane 0.333333 h;
参考文献
Tetrahedron, , vol. 37, p. 363 - 369
反应条件
1: pyridine / 0 °C 2: 1N NaOH / dioxane / 0.33 h View Scheme
参考文献
Tetrahedron, , vol. 37, p. 363 - 369
反应条件
in water Addition; Elimination; pH=5 - 7.5;
参考文献
Chemical Research in Toxicology, , vol. 11, # 9 p. 1082 - 1088
反应条件
in phosphate buffer Addition; Elimination; pH=5 - 7.5; Product distribution;
参考文献
Chemical Research in Toxicology, , vol. 11, # 9 p. 1082 - 1088
反应条件
ammonia; methylamine in water T=65°C; 1 h; deprotection reagent; Product distribution;
参考文献
Reddy, M. P.; Hanna, N. B.; Farooqui, Firdous
Tetrahedron Letters, 1994 , vol. 35, # 25 p. 4311 - 4314
参考文献
Reddy; Hanna, Naeem B.; Farooqui, Firdous
Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1589 - 1598
反应条件
1: 85 percent / pyridine 2: 85 percent / iPr2NEt / tetrahydrofuran View Scheme
参考文献
Reddy, M. P.; Hanna, N. B.; Farooqui, Firdous
Tetrahedron Letters, 1994 , vol. 35, # 25 p. 4311 - 4314