1-甲基-4-苯基乙炔苯合成路线 （共 165 条）
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran Heating;
参考文献
Pena, Miguel A.; Perez Sestelo, Jose; Sarandeses, Luis A.
Synthesis, 2005 , # 3 art. no. Z14204SS, p. 485 - 492
反应条件
1: 40 percent / NaH / dimethylformamide / 0.33 h / 80 °C 2: 15 percent / t-BuOK / dimethylformamide / 85 °C View Scheme
参考文献
Katritzky, Alan R.; Gordeev, Mikhail F.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 11 p. 1295 - 1298
反应条件
potassium hydroxide in 1,4-dioxane
参考文献
Dombrovskii,A.V.; Taschchuk,K.G.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 1 p. 165 - 170,158 - 162
反应条件
mercury(II) oxide in benzene Heating;
参考文献
Ghosh,K.; Bhattacharya,A.J.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1977 , vol. 15B, p. 678 - 680
反应条件
1: 1.) LDA / 1.) cyclohexane, THF, - 78 deg C, 15 min, 2.) THF, - 78 deg C -> 25 deg C, 4 h 2: 78 percent / t-BuOK / dimethylformamide / 85 °C View Scheme
参考文献
Katritzky, Alan R.; Gordeev, Mikhail F.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 11 p. 1295 - 1298
反应条件
1: 44 percent / t-BuOK / 1.) THF, -10 deg C, 10 min, 2.) THF, 25 deg C, 18 h 2: 15 percent / t-BuOK / dimethylformamide / 85 °C View Scheme
参考文献
Katritzky, Alan R.; Gordeev, Mikhail F.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 11 p. 1295 - 1298
反应条件
1: CuCl2*2H2O / aq. HCl 2: KOH / dioxane View Scheme
参考文献
Dombrovskii,A.V.; Taschchuk,K.G.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 1 p. 165 - 170,158 - 162
反应条件
1: CuCl2*2H2O / aq. HCl 2: KOH / dioxane View Scheme
参考文献
Dombrovskii,A.V.; Taschchuk,K.G.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 1 p. 165 - 170,158 - 162
反应条件
1: triphenylphosphine / dichloromethane / 0 °C 2: copper(l) iodide; 8-hydroxy-quinoline; potassium phosphate / ethanol / 12 h / 100 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Liu, Jidan; Dai, Fenglin; Yang, Zhiyong; Wang, Sizhuo; Xie, Kai; Wang, Anwei; Chen, Xiang; Tan, Ze
Tetrahedron Letters, 2012 , vol. 53, # 42 p. 5678 - 5683
反应条件
1: potassium tert-butylate / tetrahydrofuran / 5 h / |Inert atmosphere; |Reflux 2: tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium(0) / tetrahydrofuran / 4 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Peng, Lifen; Xu, Feng; Suzuma, Yoshinori; Orita, Akihiro; Otera, Junzo
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12802 - 12808
