2,5-二氢-3-甲基-1-[(4-甲基苯基)磺酰基]-1H-吡咯-2-羧酸乙酯合成路线 （共 3 条）
反应条件
pyridine; trichlorophosphate T=20°C;
参考文献
SEPRACOR INC.
Patent: US2005/143443 A1, 2005 ;
Location in patent: Page/Page column 39-40 ;
反应条件
1: pyridine / dichloromethane / 20 °C / |Cooling with ice 2: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 72 h / 20 °C / |Cooling with ice 3: pyridine; trichlorophosphate / 72 h / 20 °C / |Cooling with ice View Scheme
参考文献
Dainippon Sumitomo Pharma Co., Ltd.; HORIUCHI, Yoshihiro; FUJIWARA, Hiroaki; SUDA, Hitoshi; SASAKI, Izumi; IWATA, Mitsutaka; SAWAMURA, Kiyoto
Patent: EP2612848 A1, 2013 ;
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran Heating / reflux;
参考文献
SEPRACOR INC.
Patent: US2005/143443 A1, 2005 ;
Location in patent: Page/Page column 39-41 ;
