7-硝基-1,2,3,4-四氢-1-萘酚合成路线 （共 4 条）
反应条件
1: With BH3*SMe2 in tetrahydrofuran T=20°C; 15 h; 2: With methanol in tetrahydrofuran T=0°C;
参考文献
Gross, Michael F.; Castle, Neil A.; Zou, Anruo; Wickenden, Alan D.; Yu, Weifeng; Spear, Kerry L.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 11 p. 3063 - 3066
反应条件
1: 33.3 percent / NH4NO3, trifluoroacetic anhydride / CHCl3 / 2.5 h / 25 - 30 °C 2: 92.1 percent / NaBH4 / aq. ethanol / 1.5 h / Ambient temperature View Scheme
参考文献
Nichols, David E.; Cassady, John M.; Persons, Paul E.; Yeung, Ming C.; Clemens, James A.; Smalstig, E. Barry
Journal of Medicinal Chemistry, 1989 , vol. 32, # 9 p. 2128 - 2134
反应条件
1: 91.3 percent / Amberlyst 15 cation-exchange resin / benzene / 2 h / Heating 2: 89.5 percent / 85percent m-chloroperoxybenzoic acid / CHCl3 / 0.67 h / Heating 3: 83 percent / ZnI2 / benzene / 15 h / Ambient temperature View Scheme
参考文献
Nichols, David E.; Cassady, John M.; Persons, Paul E.; Yeung, Ming C.; Clemens, James A.; Smalstig, E. Barry
Journal of Medicinal Chemistry, 1989 , vol. 32, # 9 p. 2128 - 2134
反应条件
1: zinc-powder; aq.-ethanolic NH4Cl / Erwaermen des Reaktionsgemisches mit wss. H2SO4 auf dem Dampfbad
2: glacial acetic acid; palladium/charcoal / 25 °C / Hydrogenation
View Scheme
参考文献
Asahina; Momose
Yakugaku Zasshi, 1944 , vol. 64, # 3 p. 153
Chem.Abstr., 1951 , p. 5140
