3-氨基-5-三氟甲基苯甲酸合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethanol T=20°C; P=760.051 Torr; 7 h;
参考文献
Shirai, Junya; Morimoto, Shinji; Sugiyama, Hideyuki; Sakauchi, Nobuki; Yoshikawa, Takeshi
Patent: US2008/275085 A1, 2008 ;
Location in patent: Page/Page column 45 ;
US 20080275085 A1
反应条件
palladium monocarbide in ethanol
反应条件
1: With sulfuric acid in water 2: With sodium nitrite in water T=-10 - 0°C; 1.66667 h; Heating / reflux;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2007/64045 A1, 2007 ;
Location in patent: Page/Page column 341-342 ;
WO 2007/064045 A1
反应条件
1: With hydrogen bromide; sodium nitrite in water T=0°C; 1 h; 2: With copper(ll) bromide in water T=20°C; 16 h;
参考文献
Pfizer Inc
Patent: US2007/213371 A1, 2007 ;
Location in patent: Page/Page column 70 ;
