1.1: 100 percent / SOCl2 / 3 h / Heating
2.1: Ac2O / 2 h / 55 °C
2.2: CH2Cl2 / 2 h / 20 °C
3.1: 91 percent / POCl3; Et3N / tetrahydrofuran / 2 h / 0 °C
View Scheme
参考文献
Elders, Niels; Schmitz, Rob F.; De Kanter, Frans J. J.; Ruijter, Eelco; Groen, Marinus B.; Orru, Romano V. A.
Journal of Organic Chemistry, 2007 , vol. 72, # 16 p. 6135 - 6142
in isopropyl alcohol; benzene
byproducts: C3H7OH; repeated crystn., elem. anal.;
参考文献
Misra, Sudhindra N.; Joshi, G. K.; Bhutra, M. P.
Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical, 1982 , vol. 21, # 3 p. 275 - 278
Nicolaides, E. D.; Tinney, F. J.; Kaltenbronn, J. S.; Repine, J. T.; DeJohn, D. A.; et al.
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 959 - 971
