5-溴-2-氯嘧啶合成路线

参考文献

Zhang, Zaihui; Sun, Shaoyi; Kodumuru, Vishnumurthy; Hou, Duanjie; Liu, Shifeng; Chakka, Nagasree; Sviridov, Serguei; Chowdhury, Sultan; McLaren, David G.; Ratkay, Leslie G.; Khakh, Kuldip; Cheng, Xing; Gschwend, Heinz W.; Kamboj, Rajender; Fu, Jianmin; Winther, Michael D.
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38275-57-95-溴-2-氰基嘧啶

参考文献

GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; DRAGOVICH, Peter; GOSSELIN, Francis; YUEN, Po-Wai; ZAK, Mark; ZHENG, Xiaozhang
Patent: WO2013/127267 A1, 2013 ;
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506-59-2盐酸二甲胺+

32779-36-55-溴-2-氯嘧啶

38696-21-85-溴-2-(二甲基氨基)嘧啶

参考文献

Plant, Andrew; Seitz, Thomas; Jansen, Johannes Rudolf; Erdelen, Christoph; Turberg, Andreas; Hansen, Olaf
Patent: US2004/82586 A1, 2004 ;

32779-36-55-溴-2-氯嘧啶+

124-40-3二甲胺

38696-21-85-溴-2-(二甲基氨基)嘧啶

参考文献

Burger, Matthew T.; Knapp, Mark; Wagman, Allan; Ni, Zhi-Jie; Hendrickson, Thomas; Atallah, Gordana; Zhang, Yanchen; Frazier, Kelly; Verhagen, Joelle; Pfister, Keith; Ng, Simon; Smith, Aaron; Bartulis, Sarah; Merrit, Hanne; Weismann, Marion; Xin, Xiaohua; Haznedar, Joshua; Voliva, Charles F.; Iwanowicz, Ed; Pecchi, Sabina
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32779-36-55-溴-2-氯嘧啶

14305-25-0

参考文献

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32779-36-55-溴-2-氯嘧啶+

99-76-3对羟基苯甲酸甲酯

926304-76-95-溴-2-[(4-甲氧基羰基)苯氧基]嘧啶

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WO 2007/022371 A2

5720-07-04-甲氧基苯硼酸+

32779-36-55-溴-2-氯嘧啶

27794-03-25-（4-甲氧基苯基）-2-氯嘧啶