N-t-叔丁氧羰基-2S-1S-丁基二甲基硅烷基氧基-2-氯乙基)氮丙啶合成路线 （共 5 条）
反应条件
1: 75 percent / CuBr*Me2S / toluene; tetrahydrofuran / -78 - -20 °C 2: Bu4NF / tetrahydrofuran View Scheme
参考文献
Organic letters, , vol. 3, # 15 p. 2349 - 2351
反应条件
1: 75 percent / CuBr*Me2S / toluene; tetrahydrofuran / -78 - -20 °C 2: Bu4NF / tetrahydrofuran 3: 90 percent / propan-2-ol / 5 h / 50 °C 4: 88 percent / Et3N / CH2Cl2 / 12 h / 20 °C View Scheme
参考文献
Kim; Bae; So; Yoo; Chang; Lee; Kang
Organic letters, 2001 , vol. 3, # 15 p. 2349 - 2351
反应条件
1: 75 percent / CuBr*Me2S / toluene; tetrahydrofuran / -78 - -20 °C 2: Bu4NF / tetrahydrofuran View Scheme
参考文献
Organic letters, , vol. 3, # 15 p. 2349 - 2351
反应条件
1: 75 percent / CuBr*Me2S / toluene; tetrahydrofuran / -78 - -20 °C 2: Bu4NF / tetrahydrofuran 3: 90 percent / propan-2-ol / 5 h / 50 °C View Scheme
参考文献
Kim; Bae; So; Yoo; Chang; Lee; Kang
Organic letters, 2001 , vol. 3, # 15 p. 2349 - 2351
反应条件
1.1: 75 percent / CuBr*Me2S / toluene; tetrahydrofuran / -78 - -20 °C
2.1: Bu4NF / tetrahydrofuran
3.1: 90 percent / propan-2-ol / 5 h / 50 °C
4.1: 88 percent / Et3N / CH2Cl2 / 12 h / 20 °C
5.1: HCl(g) / CH2Cl2 / 1.5 h
5.2: 85 percent / Et3N / CH2Cl2 / 4 h / 20 °C
View Scheme
参考文献
Kim; Bae; So; Yoo; Chang; Lee; Kang
Organic letters, 2001 , vol. 3, # 15 p. 2349 - 2351
