1,3-苯并二氧戊环-5-基乙酸酯合成路线 （共 14 条）
反应条件
tin(IV) chloride in dichloromethane
T=0°C; Friedel-Crafts type formylation; 2 h;
参考文献
Cueva, Juan Pablo; Chemel, Benjamin R.; Juncosa Jr., Jose I.; Lill, Markus A.; Watts, Val J.; Nichols, David E.
European Journal of Medicinal Chemistry, 2012 , vol. 48, p. 97 - 107
反应条件
1: 1 h / 50 °C / Inert atmosphere; Neat (no solvent); Sealed tube
2: zinc(II) chloride / 1,4-dioxane / 192 h / 100 °C / Inert atmosphere
View Scheme
参考文献
Jerezano, Alberto; Jimenez, Fabiola; Del Carmen Cruz, Maria; Montiel, Luisa E.; Delgado, Francisco; Tamariz, Joaquin
Helvetica Chimica Acta, 2011 , vol. 94, # 2 p. 185 - 198
反应条件
bromine; acetic acid
参考文献
Alexander et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 1969
反应条件
1: acetic acid; aqueous nitric acid
2: sodium methylate; methanol
3: pyridine; benzene
View Scheme
参考文献
Gertler et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 327
