甲基 1,3-苯并二恶唑-5-羧酸酯合成路线 （共 49 条）
反应条件
sulfuric acid 12 h; Heating;
参考文献
Anderson, Karen; Kuruvilla, Alice; Uretsky, Norman; Miller, Duane D.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 683 - 687
反应条件
potassium hydroxide; iodine in methanol T=0°C; 1.5 h;
参考文献
University of Maryland
Patent: US7091238 B1, 2006 ;
Location in patent: Page/Page column 7-8; 11-13 ;
反应条件
tellurium; Bi(NO3)3·5H2O; 5 palladium on charcoal; oxygen in methanol T=60°C; P=760.051 Torr; 8 h;
参考文献
Powell, Adam B.; Stahl, Shannon S.
Organic Letters, 2013 , vol. 15, # 19 p. 5072 - 5075
反应条件
potassium hydroxide; iodine T=0°C; Oxidation; Yamada reaction; 1.5 h;
参考文献
Kuemmerle, Arthur E.; Raimundo, Juliana M.; Leal, Carla M.; da Silva, Givanildo S.; Balliano, Tatiane L.; Pereira, Mariano A.; de Simone, Carlos A.; Sudo, Roberto T.; Zapata-Sudo, Gisele; Fraga, Carlos A.M.; Barreiro, Eliezer J.
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 10 p. 4004 - 4009
反应条件
triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in acetonitrile T=80°C; 0.25 h; microwave irradiation;
参考文献
Organic Letters, , vol. 9, # 18 p. 3683 - 3685
反应条件
dihydrogen peroxide; sulfuric acid in methanol 24 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 49, # 24 p. 4740 - 4741
反应条件
ethylaluminum dichloride in dichloromethane T=-78 - 20°C; Disproportionation; 1 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 71, # 9 p. 2181 - 2185
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydrogencarbonate in acetonitrile T=120°C; Inert atmosphere;
参考文献
Tetrahedron, , vol. 65, # 48 p. 10009 - 10015
反应条件
potassium carbonate in dimethyl sulfoxide T=90°C; 16 h; Inert atmosphereGreen chemistry;
参考文献
Ji, Yuan; Sweeney, Jessica; Zoglio, Jillian; Gorin, David J.
Journal of Organic Chemistry, 2013 , vol. 78, # 22 p. 11606 - 11611
反应条件
1: 93 percent / pyridinium chlorochromate / CH2Cl2 / 16 h / 18 °C 2: 88 percent / acetic acid; sodium cyanide; MnO2 / CHCl3 / 16 h / 18 °C 3: 24 percent / triethylamine / PdCl2(dppf) / acetonitrile / 0.25 h / 80 °C / microwave irradiation View Scheme
参考文献
Organic Letters, , vol. 9, # 18 p. 3683 - 3685
