5-三氟甲基-1H-苯并咪唑合成路线 （共 5 条）
参考文献
PHARMACOPEIA DRUG DISCOVERY, INC.
Patent: WO2004/69829 A1, 2004 ;
Location in patent: Page 18 ;
反应条件
RuCl2(dppe)2; hydrogen T=120°C; P=112511 Torr; 40 h; Green chemistry;
参考文献
Yu, Bo; Zhang, Hongye; Zhao, Yanfei; Chen, Sha; Xu, Jilei; Huang, Changliang; Liu, Zhimin
Green Chemistry, 2013 , vol. 15, # 1 p. 95 - 99
反应条件
tin(ll) chloride T=130°C; 0.0833333 h; microwave;
参考文献
VanVliet, David S.; Gillespie, Paul; Scicinski, Jan J.
Tetrahedron Letters, 2005 , vol. 46, # 39 p. 6741 - 6743
反应条件
in methanol 168 h; Ambient temperatureIrradiation; Title compound not separated from byproducts;
参考文献
Kimoto, Hiroshi; Fujii, Shozo; Cohen, Louis A.
Journal of Organic Chemistry, 1982 , vol. 47, # 15 p. 2867 - 2872
反应条件
1: SnCl2; aq.-ethanolic HCl 2: aqueous HCl View Scheme
参考文献
Sykes; Tatlow
Journal of the Chemical Society, 1952 , p. 4078
