3-溴-呋喃-2-羧酸乙酯合成路线 （共 4 条）
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in ethanol; dichloromethane T=25°C; 5 h;
参考文献
DAINIPPON PHARMACEUTICAL CO., LTD.
Patent: EP1489077 A1, 2004 ;
Location in patent: Page 29 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide T=60°C;
参考文献
Taniguchi, Takahiko; Suzuki, Shinkichi; Yoshikawa, Masato; Hasui, Tomoaki; Fushimi, Makoto; Kunitomo, Jun
Patent: US2013/137675 A1, 2013 ;
Location in patent: Paragraph 0599 ;
反应条件
sodium peroxodisulphate; N-bromosuccinmide; trifluorormethanesulfonic acid; palladium diacetate in 1,2-dichloro-ethane T=60°C; 2 h; Sealed tube; regioselective reaction;
参考文献
Sun, Xiuyun; Shan, Gang; Sun, Yonghui; Rao, Yu
Angewandte Chemie - International Edition, 2013 , vol. 52, # 16 p. 4440 - 4444
Angew. Chem., 2013 , vol. 125, # 16 p. 4536 - 4540,5
反应条件
1: sodium chlorite; sodium dihydrogenphosphate / tert-butyl alcohol; water / 20 °C 2: potassium carbonate / N,N-dimethyl-formamide / 60 °C View Scheme
参考文献
Taniguchi, Takahiko; Suzuki, Shinkichi; Yoshikawa, Masato; Hasui, Tomoaki; Fushimi, Makoto; Kunitomo, Jun
Patent: US2013/137675 A1, 2013 ;
