α-甲苯磺酰-(3,4,5-三甲氧基l苄基)异丁酯合成路线 （共 5 条）
反应条件
triethylamine; trichlorophosphate in ethylene glycol dimethyl ether T=-10 - -5°C; 2 h;
参考文献
UNIWERSYTET MEDYCZNY IM. KAROLA MARCINKOWSKIEGO; STEFAŃSKI, Tomasz; RÓŻAŃSKI, Jakub; MIKSTACKA, Renata; SOBIAK, Stanisław
Patent: WO2013/147629 A1, 2013 ;
Location in patent: Page/Page column 13 ;
反应条件
1: 47 percent / 10-camphorsulfonic acid / 16 h / 65 °C 2: 69 percent / POCl3; Et3N / 1,2-dimethoxy-ethane / 3 h / -5 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 8 p. 1697 - 1711
反应条件
1: 47 percent / 10-camphorsulfonic acid / 16 h / 65 °C 2: 69 percent / POCl3; Et3N / 1,2-dimethoxy-ethane / 3 h / -5 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 8 p. 1697 - 1711
反应条件
1: (+)-10-camphorsulfonic acid / formamide / 16 h / 60 °C 2: trichlorophosphate; triethylamine / ethylene glycol dimethyl ether / 2 h / -10 - -5 °C View Scheme
反应条件
1: camphor-10-sulfonic acid / 16 h / 65 °C 2: trichlorophosphate; triethylamine / ethylene glycol dimethyl ether / 3 h / -10 - -5 °C View Scheme
参考文献
Medicinal Chemistry Research, , vol. 22, # 12 p. 5654 - 5669
