5-噻吩-2-基-2-糠醛合成路线 （共 7 条）
反应条件
triethylamine; palladium on activated charcoal in ethanol T=60°C; Suzuki cross-coupling reaction; 36 h;
参考文献
McClure; Roschangar; Hodson; Millar; Osterhout
Synthesis, 2001 , # 11 p. 1681 - 1685
反应条件
hydrogenchloride; water in tetrahydrofuran T=20°C; 16 h;
参考文献
US6642237 B1, ;
Page/Page column 128 ;
反应条件
caesium carbonate; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane T=95°C; Suzuki-Miyaura cross-coupling reaction; 91 h;
参考文献
Parry, Paul R.; Bryce, Martin R.; Tarbit, Brian
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 9 p. 1447 - 1449
反应条件
1: With palladium diacetate; xantphos in N-dodecane; butan-1-ol T=25°C; Suzuki-Miyaura Coupling; 1 h; Inert atmosphereGlovebox; 2: With cesium hydroxide monohydrate in N-dodecane; water; butan-1-ol T=80°C; Suzuki-Miyaura Coupling; 4 h; Inert atmosphereGlovebox;
参考文献
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259,12
Title/Abstract Full Text Show Details
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259
反应条件
palladium diacetate; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in water; acetonitrile T=25°C; Suzuki Coupling; Inert atmosphere;
参考文献
Lin, Jinshun; Jin, Xiuli; Bu, Yiwen; Cao, Deliang; Zhang, Nannan; Li, Shangfu; Sun, Qinsheng; Tan, Chunyan; Gao, Chunmei; Jiang, Yuyang
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9734 - 9746
反应条件
tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane T=80 - 90°C; Stille coupling; 24 h;
参考文献
Ismail, Mohamed A.
Journal of Chemical Research, 2006 , # 11 p. 733 - 737
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 5 h / -78 °C 1.2: trimethylborate / tetrahydrofuran; hexane / -78 - 25 °C 1.3: 52 percent / aq. NaOH / pH 10 2.1: 61 percent / Cs2CO3 / Pd(PPh3)2Cl2 / dioxane / 91 h / 95 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 1, # 9 p. 1447 - 1449
