1-(3-氯-2-羟苯基)乙基-1-酮合成路线 （共 11 条）
反应条件
AlCl3, aluminium chloride in 1,2-dichloro-benzene T=20 - 100°C; Fries Phenol Ester Rearrangement; 5 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 58, p. 184 - 191
反应条件
potassium hydroxide; iodobenzene diacetate in methanol; diethyl ether; ethanol; water
反应条件
sodium perborate in acetic acid deoximation; 5.5 h; Heating;
参考文献
Hangarge; Mane; Chavan; Shingare
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 6 p. 1302 - 1304
反应条件
boron tribromide in dichloromethane T=-78 - 23°C; 1 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 1 p. 619 - 622
反应条件
2,2,6,6-tetramethyl-piperidine; sulfuryl dichloride T=100°C; 0.75 h; Inert atmosphere; regioselective reaction;
参考文献
Saper, Noam I.; Snider, Barry B.
Journal of Organic Chemistry, 2014 , vol. 79, # 2 p. 809 - 813
反应条件
1: pyridine / dichloromethane / 4 h / 20 - 25 °C 2: AlCl3, aluminium chloride / 1,2-dichloro-benzene / 5 h / 20 - 100 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 58, p. 184 - 191
反应条件
aluminium trichloride; Petroleum ether und Erwaermen des Reaktionsprodukts mit wss.KOH;
参考文献
Journal of the Indian Chemical Society, , vol. 26, p. 366,367
反应条件
1: 89 percent / aq.NaOH / 1 h / 0 °C 2: AlCl3 / 1.) to 110 deg C, 1 h, 2.) 150 deg C, 2 h View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 11 p. 2713 - 2739
反应条件
1: pyrrolidine / methanol / 24 h / 20 °C 2: hydrogenchloride / ethyl acetate / 2 h / 20 °C View Scheme
参考文献
Chaudhari, Sachin S.; Kadam, Ashok B.; Khairatkar-Joshi, Neelima; Mukhopadhyay, Indranil; Karnik, Pallavi V.; Raghuram, Anupindi; Rao, Shobha S.; Vaiyapuri, Thamil Selvan; Wale, Dinesh P.; Bhosale, Vikram M.; Gudi, Girish S.; Sangana, Ramchandra R.; Thomas, Abraham
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 21 p. 6542 - 6553
反应条件
1: K2CO3; acetone 2: KMnO4; aqueous NaOH View Scheme
参考文献
Shah; Parikh
Journal of the Indian Chemical Society, 1959 , vol. 36, p. 784
