(S)-4-(2-羟乙基)-2,2-二甲基-1,3-二氧戊环合成路线 （共 49 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 5 h;
参考文献
Tursun, Ahmatjan; Canet, Isabelle; Aboab, Bettina; Sinibaldi, Marie-Eve
Tetrahedron Letters, 2005 , vol. 46, # 13 p. 2291 - 2294
反应条件
p-toluenesulfonic acid monohydrate; sodium carbonate in acetone
参考文献
Daiso Co., Ltd.
Patent: US6620977 B1, 2003 ;
反应条件
toluene-4-sulfonic acid; copper(II) sulfate T=20°C; 72 h;
参考文献
Nilewski, Christian; Deprez, Nicholas R.; Fessard, Thomas C.; Li, Dong Bo; Geisser, Roger W.; Carreira, Erick M.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 34 p. 7940 - 7943
反应条件
sodium sulfate; toluene-4-sulfonic acid in 1,4-dioxane; methanol; ethyl acetate; acetone
参考文献
Bio-Rad Laboratories Inc.
Patent: US2003/191074 A1, 2003 ;
反应条件
toluene-4-sulfonic acid in dichloromethane T=20°C; 4 h; Inert atmosphere;
参考文献
Venkanna, Arramshetti; Sreedhar, Eppakayala; Siva, Bandi; Babu, Katragadda Suresh; Prasad, Kothakonda Rajendra; Rao, Janaswamy Madhusudana
Tetrahedron Asymmetry, 2013 , vol. 24, # 17 p. 1010 - 1022
反应条件
lithium aluminium tetrahydride in diethyl ether 1.) room temperature, 12 h, 2.) reflux, 1 h;
参考文献
Saibaba, Rasha; Sarma, Mallela S. P.; Abushanab, Elie
Synthetic Communications, 1989 , vol. 19, # 17 p. 3077 - 3086
反应条件
potassium carbonate in methanol T=23°C; 18 h;
参考文献
Meyers, A.I.; Lawson, Jon P.
Tetrahedron Letters, 1982 , vol. 23, # 47 p. 4883 - 4886
反应条件
potassium borohydride; magnesium chloride in tetrahydrofuran T=66°C; 2 h;
参考文献
Qiu, You-Chun; Zhang, Fu-Li; Zhang, Chun-Nian
Tetrahedron Letters, 2007 , vol. 48, # 43 p. 7595 - 7598
反应条件
1: (-)-(S)-hydroxybutanedioic acid With dimethylsulfide borane complex in tetrahydrofuran T=0 - 20°C; 15 h; 2: acetone With toluene-4-sulfonic acid T=20°C; 17 h;
参考文献
Lastdrager, Bas; Timmer, Mattie S. M.; Van Der Marel, Gijsbert A.; Overkleeft, Herman S.
Tetrahedron Letters, 2005 , vol. 46, # 37 p. 6195 - 6198
反应条件
potassium borohydride; magnesium chloride in tetrahydrofuran T=25°C; 0.5 h;
参考文献
Qiu, You-Chun; Zhang, Fu-Li; Zhang, Chun-Nian
Tetrahedron Letters, 2007 , vol. 48, # 43 p. 7595 - 7598
