8-甲氧基-1,2,3,4-四氢萘-2-甲酸合成路线 （共 15 条）
反应条件
Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 49, # 26 p. 5116 - 5124
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Liu, Bo; Liu, Gang; Nelson, Lisa T.J.; Patel, Jyoti R.; Sham, Hing L.; Xin, Zhili; Zhao, Hongyu
Patent: US2005/14794 A1, 2005 ;
Location in patent: Page 24 ;
US 20050014794 A1
反应条件
1: 75 percent / diphenylphosphoryl azide, Et3N / 18 h / Heating
2: 74 percent / 4N HCl / ethyl acetate / 3 h
View Scheme
参考文献
Langlois; Gaudy
Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734
反应条件
AlCl3, aluminium chloride in toluene
2 h; RefluxInert atmosphere;
参考文献
Zhang, Yong-Kang; Plattner, Jacob J.; Freund, Yvonne R.; Easom, Eric E.; Zhou, Yasheen; Ye, Long; Zhou, Huchen; Waterson, David; Gamo, Francisco-Javier; Sanz, Laura M.; Ge, Min; Li, Zhiya; Li, Lingchao; Wang, Hailong; Cui, Han
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 3 p. 1299 - 1307
反应条件
1: 75 percent / diphenylphosphoryl azide, Et3N / 18 h / Heating
2: 74 percent / 4N HCl / ethyl acetate / 3 h
3: 66 percent / K2CO3 / acetonitrile / 96 h / Ambient temperature
View Scheme
参考文献
Langlois; Gaudy
Synthetic Communications, 1992 , vol. 22, # 12 p. 1723 - 1734
