2-二氯甲基-4,5-二氢噻唑-4-羧酸甲酯合成路线 （共 2 条）
反应条件
1: α,α-dichloroacetonitrile With sodium methylate in methanol T=-15°C; 0.916667 h; 2: (L)-cysteine methyl ester hydrochloride in methanol T=20°C;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/5998 A1, 2009 ;
Location in patent: Page/Page column 238 ;
反应条件
sodium methylate T=20°C; 12 h;
参考文献
Aditya, Animesh; Kodadek, Thomas
ACS Combinatorial Science, 2012 , vol. 14, # 3 p. 164 - 169
