2-氟-联苯-4-胺盐酸盐合成路线 （共 3 条）
反应条件
potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in ethylene glycol dimethyl ether; ethanol; water T=110°C; Suzuki-Miyaura coupling; 1 h; Microwave irradiation;
参考文献
Birch, Alan M.; Groombridge, Sam; Law, Robert; Leach, Andrew G.; Mee, Christine D.; Schramm, Carolin
Journal of Medicinal Chemistry, 2012 , vol. 55, # 8 p. 3923 - 3933
反应条件
(i) PCl5, benzene, (ii) aq. HCl, EtOH; Multistep reaction;
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
反应条件
sulfuric acid; acetic acid 2.) reflux, 30 min; Yield given. Multistep reaction;
参考文献
Byron, D. J.; Lacey, D.; Wilson, R. C.
Molecular Crystals and Liquid Crystals (1969-1991), 1981 , vol. 73, p. 273 - 282
