2-甲基-4-苯基-1,3-噻唑-5-羧酸乙酯合成路线 （共 4 条）
参考文献
Platonova; Volkova; Malin; Veretennikov; Laskin
Russian Journal of Applied Chemistry, 2008 , vol. 81, # 3 p. 513 - 515
反应条件
1: ethyl 3-oxo-3-phenylpropionate With PhI(ODNs)OH in acetonitrile T=120°C; 0.00833333 h; 2: ethanethioamide in acetonitrile 0.0166667 h; Microwave irradiation;
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 22 p. 9008 - 9018
反应条件
potassium hydroxide in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol; water
参考文献
NIHON NOHYAKU CO., LTD.
Patent: EP761658 A1, 1997 ;
反应条件
1: 87 percent / sodium hydroxide / methanol; H2O / 20 °C
2: thionyl chloride / toluene / Heating
3: pyridine / CH2Cl2 / 0 °C
View Scheme
参考文献
Herrero, M.Teresa; Tellitu, Imanol; Dominguez, Esther; Hernandez, Susana; Moreno, Isabel; SanMartin, Raul
Tetrahedron, 2002 , vol. 58, # 42 p. 8581 - 8589
