4-溴甲基-2-氯-1-甲氧基苯合成路线 （共 7 条）
反应条件
azobisisobutyronitrile in N-bromosuccinmide; water
参考文献
Chackalamannil, Samuel; Wang, Yuguang; Boyle, Craig D.; Stamford, Andrew W.
Patent: US2002/169174 A1, 2002 ;
US 20020169174 A1
参考文献
Journal of the Chemical Society, , p. 1780,1782
反应条件
1: aqueous NaOH / 50 °C 2: aqueous HBr View Scheme
参考文献
Journal of the Chemical Society, , p. 1780,1782
反应条件
T=26.85°C; bromide-transfer; gas phase; low pressure; Thermodynamic data; Further Variations:Reaction partners;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 71, # 6 p. 1401 - 1407
反应条件
T=26.85°C; bromide-transfer; gas phase; low pressure; Thermodynamic data; Further Variations:Reaction partners;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 71, # 6 p. 1401 - 1407
反应条件
sodium cyanide in ethanol; water
T=20°C;
参考文献
Roche Palo Alto LLC
Patent: US2007/88053 A1, 2007 ;
Location in patent: Page/Page column 19 ;
反应条件
1: With thiourea in ethanol
16 h; Heating / reflux;
2: With sodium hydroxide in water
T=80°C; 1 h;
3: With hydrogenchloride in water
T=0°C;
参考文献
AstraZeneca UK Limited
Patent: EP1348709 A2, 2003 ;
Location in patent: Page/Page column 14-15 ;
