4-(3-甲氧基苯基)吗啉合成路线 (共 24 条)
反应条件
bis(1,5-cyclooctadiene)nickel (0); sodium t-butanolate; IPr*hydrochloride in toluene T=100°C; 20 h; Inert atmosphereSchlenk technique;
参考文献
Zhu, Feng; Wang, Zhong-Xia
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 18 p. 3694 - 3702
反应条件
1: tris(3-methoxyphenyl)boronic acid anhydride With potassium carbonate in 1,4-dioxane T=130°C; 24 h; Inert atmosphere; 2: morpholino benzoate in 1,4-dioxane Inert atmosphere;
参考文献
Xiao, Qing; Tian, Leiming; Tan, Renchang; Xia, Ying; Qiu, Di; Zhang, Yan; Wang, Jianbo
Organic Letters, 2012 , vol. 14, # 16 p. 4230 - 4233
反应条件
iron(III) oxide; L-proline; sodium t-butanolate in dimethyl sulfoxide T=135°C; 24 h;
参考文献
Quo, Diliang; Huang, He; Xu, Jinyi; Jiang, Hualiang; Liu, Hong
Organic Letters, 2008 , vol. 10, # 20 p. 4513 - 4516
反应条件
manganese(II) chloride tetrahydrate; L-proline; sodium t-butanolate in dimethyl sulfoxide T=135°C; 24 h;
参考文献
Yong, Fui-Fong; Teo, Yong-Chua
Tetrahedron Letters, 2010 , vol. 51, # 30 p. 3910 - 3912
反应条件
bicyclo-[2.2.1]hept-2-ene; tris(4-methoxyphenyl)-phosphine; palladium diacetate; caesium carbonate; isopropyl alcohol in toluene T=100°C; 24 h; Inert atmosphereSealed tube;
参考文献
Dong, Zhe; Dong, Guangbin
Journal of the American Chemical Society, 2013 , vol. 135, # 49 p. 18350 - 18353
反应条件
sodium hydroxide in acetonitrile T=70°C;
参考文献
Ge, Jian-Feng; Arai, Chika; Kaiser, Marcel; Wittlin, Sergio; Brun, Reto; Ihara, Masataka
Journal of Medicinal Chemistry, 2008 , vol. 51, # 12 p. 3654 - 3658
反应条件
bis(1,5-cyclooctadiene)nickel (0); Ipr.HCl; sodium t-butanolate in 1,4-dioxane T=25°C; 5 h; Molecular sieveSchlenk technique; Catalytic behavior; Reagent/catalystSolventTemperatureTime;
参考文献
Zhang, Xue-Qi; Wang, Zhong-Xia
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 9 p. 1448 - 1453
参考文献
Gilman; Kyle
Journal of the American Chemical Society, 1952 , vol. 74, p. 3027
参考文献
Gilman; Kyle
Journal of the American Chemical Society, 1952 , vol. 74, p. 3027
反应条件
potassium hexamethylsilazane in 1,4-dioxane T=100°C; metal-free Buchwald-Hartwig amination; 0.166667 h; Inert atmosphere;
参考文献
Bolliger, Jeanne L.; Frech, Christian M.
Tetrahedron, 2009 , vol. 65, # 6 p. 1180 - 1187