(S)-(+)-2-甲基哌啶合成路线 (共 25 条)
反应条件
1: toluene / Heating 2: Et3SiH, TiCl4 3: 80 percent / Na, liq. NH3 4: 55 percent / AlH3 View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 6, # 11 p. 2651 - 2654
反应条件
1: 77 percent / sodium cyanoborohydride / pH = 3 2: H2 / Pd-C / methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 39 p. 6329 - 6332
参考文献
Freville; Celerier; Thuy; Lhommet
Tetrahedron Asymmetry, 1995 , vol. 6, # 11 p. 2651 - 2654
反应条件
methoxybenzene; trifluoroacetic acid in dichloromethane Decarboxylation;
参考文献
Tetrahedron Letters, , vol. 41, # 45 p. 8769 - 8772
反应条件
1: H2; Pd(OH)2 / methanol 2: TFA; anisole / CH2Cl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 45 p. 8769 - 8772
反应条件
1: NaBH4 / benzene; toluene; methanol / Irradiation 2: 91 percent / LiAlH4 / tetrahydrofuran / Heating 3: H2; Pd(OH)2 / methanol 4: TFA; anisole / CH2Cl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 45 p. 8769 - 8772
反应条件
1: 91 percent / LiAlH4 / tetrahydrofuran / Heating 2: H2; Pd(OH)2 / methanol 3: TFA; anisole / CH2Cl2 View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 45 p. 8769 - 8772
反应条件
in dichloromethane T=5°C; Acylation; 12 h;
参考文献
Tetrahedron Letters, , vol. 41, # 13 p. 2239 - 2242
反应条件
1: 80 percent / Na, liq. NH3 2: 55 percent / AlH3 View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 6, # 11 p. 2651 - 2654
反应条件
in dichloromethane T=-20 - 5°C; 26 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , vol. 2, # 2 p. 257 - 274