(S)-(+)-2-甲基哌啶合成路线 （共 25 条）
反应条件
hydrogen; acetic acid; palladium dihydroxide T=50°C; P=75006 Torr; 22 h; Title compound not separated from byproducts;
参考文献
Angewandte Chemie - International Edition, , vol. 43, # 21 p. 2850 - 2852
反应条件
ammonium formate; palladium on activated charcoal in methanol 0.166667 h; Heating;
参考文献
Wu, Xiao-Dong; Khim, Seock-Kyu; Zhang, Xiaoming; Cederstrom, Ericka M.; Mariano, Patrick S.
Journal of Organic Chemistry, 1998 , vol. 63, # 3 p. 841 - 859
反应条件
1: 80 percent / Red-Al / tetrahydrofuran / Heating 2: DMAP / CH2Cl2 3: H2 / Pd(OH)2/C / methanol / 2280 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 60, # 22 p. 7084 - 7085
参考文献
Canadian Journal of Chemistry, , vol. 61, p. 2572 - 2580
Journal of the Chemical Society, Chemical Communications, , # 18 p. 1413 - 1415
Journal of the Chemical Society, Chemical Communications, , # 15 p. 1795 - 1796
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 12 p. 3031 - 3036
Tetrahedron Asymmetry, , vol. 8, # 8 p. 1275 - 1278
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal
参考文献
Freville; Celerier; Thuy; Lhommet
Tetrahedron Asymmetry, 1995 , vol. 6, # 11 p. 2651 - 2654
反应条件
1: 53 percent / K2CO3 / acetonitrile / 48 h / Heating 2: 61 percent / (n-Bu4N)2Ce(NO3)6 / acetonitrile / 18 h / 25 °C 3: 28 percent / HCOONH4 / Pd/C / methanol / 0.17 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 3 p. 841 - 859
反应条件
1: 92 percent / K2CO3 / dimethylformamide / 12 h / 25 °C 2: 80 percent / Na/Hg, Na2HPO4 / methanol / 12 h / Heating 3: 53 percent / K2CO3 / acetonitrile / 48 h / Heating 4: 61 percent / (n-Bu4N)2Ce(NO3)6 / acetonitrile / 18 h / 25 °C 5: 28 percent / HCOONH4 / Pd/C / methanol / 0.17 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 3 p. 841 - 859
反应条件
1: 61 percent / (n-Bu4N)2Ce(NO3)6 / acetonitrile / 18 h / 25 °C 2: 28 percent / HCOONH4 / Pd/C / methanol / 0.17 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 3 p. 841 - 859
反应条件
1: 80 percent / Na/Hg, Na2HPO4 / methanol / 12 h / Heating 2: 53 percent / K2CO3 / acetonitrile / 48 h / Heating 3: 61 percent / (n-Bu4N)2Ce(NO3)6 / acetonitrile / 18 h / 25 °C 4: 28 percent / HCOONH4 / Pd/C / methanol / 0.17 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 3 p. 841 - 859
反应条件
1: 98 percent / H2 / Pd(OH)2/C / methanol / 24 h / 20 °C / 3800 Torr 2: LiAlH4 / diethyl ether; tetrahydrofuran / 12 h / Heating View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 9 p. 1387 - 1394
