3-氨基-5-甲基-4-苯基吡唑合成路线 （共 7 条）
反应条件
hydrazine hydrate; acetic acid in ethanol T=50°C; 7 h; Reflux;
参考文献
Emelina; Petrov; Filyukov
Russian Journal of Organic Chemistry, 2014 , vol. 50, # 3 p. 412 - 421
Zh. Org. Khim., 2014 , vol. 50, # 3 p. 424 - 433,10
反应条件
isopropylamine in methanol 3 h; Ambient temperature;
参考文献
Ege, Guenter; Gilbert, Karlheinz; Maurer, Kurt
Chemische Berichte, 1987 , vol. 120, p. 1375 - 1396
反应条件
hydrazine hydrate; acetic acid in ethanol T=50°C; 7 h; Overall yield = 73 percent;
参考文献
Petrov; Kasatochkin; Emelina
Russian Journal of Organic Chemistry, 2012 , vol. 48, # 8 p. 1111 - 1120
Zh. Org. Khim., 2012 , vol. 48, # 8 p. 1113 - 1121,9
反应条件
in dichloromethane 96 h; Ambient temperature;
参考文献
Ege, Guenter; Gilbert, Karlheinz; Maurer, Kurt
Chemische Berichte, 1987 , vol. 120, p. 1375 - 1396
反应条件
in ethanol 1.) 15 min, reflux; 2.) 10 d, RT;
参考文献
Ege, Guenter; Gilbert, Karlheinz; Maurer, Kurt
Chemische Berichte, 1987 , vol. 120, p. 1375 - 1396
反应条件
hydrogenchloride; sodium carbonate; sodium nitrite in water
T=0 - 5°C; 0.5 h;
参考文献
Ege, Guenter; Gilbert, Karlheinz; Heck, Reinhard
Chemische Berichte, 1984 , vol. 117, # 5 p. 1726 - 1747
反应条件
1: conc. HCl, NaNO2; aq. sodium carbonate / H2O / 0.5 h / 0 - 5 °C
2: 51 percent / CH2Cl2 / 1 h / 10 °C
View Scheme
参考文献
Ege, Guenter; Gilbert, Karlheinz
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 675 - 677
