2,4-二羟基-6-甲基苯甲酸甲酯合成路线 （共 72 条）
反应条件
titanium(IV) isopropylate; titanium tetrachloride in dichloromethane 1.) -78 deg C, 5 h, 2.) RT, overnight;
参考文献
Chan, T. H.; Stoessel, D.
Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2423 - 2428
反应条件
titanium tetrachloride in dichloromethane 1.) -78 deg C, 2-3 h, 2.) RT, overnight;
参考文献
Chan, T. H.; Stoessel, D.
Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2423 - 2428
反应条件
1.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C 1.2: 96 percent / tetrahydrofuran / -78 - 20 °C 2.1: 98 percent / AlCl3 / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Mondal, Mukulesh; Puranik, Vedavati G.; Argade, Narshinha P.
Journal of Organic Chemistry, 2007 , vol. 72, # 6 p. 2068 - 2076
反应条件
1.1: 99 percent / N-bromosuccinimide / CCl4 / 4 h / Heating 2.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C 2.2: 96 percent / tetrahydrofuran / -78 - 20 °C 3.1: 98 percent / AlCl3 / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Mondal, Mukulesh; Puranik, Vedavati G.; Argade, Narshinha P.
Journal of Organic Chemistry, 2007 , vol. 72, # 6 p. 2068 - 2076
反应条件
mercury(II) diacetate; sodium acetate; acetic acid 2 h; Reflux;
参考文献
Karmakar, Raju; Mal, Dipakranjan
Journal of Organic Chemistry, 2012 , vol. 77, # 22 p. 10235 - 10248
反应条件
n-butyllithium; sodium hydride in tetrahydrofuran; hexane 48 h; Heating;
参考文献
Barrett, Anthony G. M.; Morris, Timothy M.; Barton, Derek H. R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2272 - 2277
反应条件
hydrogen; palladium on activated charcoal
参考文献
Ansell,M.F.; Culling,G.C.
Journal of the Chemical Society, 1961 , p. 2908 - 2914
反应条件
sodium methylate in methanol Substitution;
参考文献
Mueller, Michael; Lamottke, Kai; Loew, Erich; Magor-Veenstra, Eva; Sieglich, Wolfgang
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 15 p. 2483 - 2489
参考文献
Honda; Pavan; Coelho; de Andrade Leite; Micheletti; Lopes; Misutsu; Beatriz; Brum; Leite
Phytomedicine, 2010 , vol. 17, # 5 p. 328 - 332
反应条件
n-butyllithium; sodium hydride in hexane 48 h; Heating;
参考文献
Barrett, Anthony G. M.; Morris, Timothy M.; Barton, Derek H. R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2272 - 2277
