2-氨基-3-甲氧基苯甲酸合成路线 (共 68 条)
反应条件
hydrogen; palladium on activated charcoal in ethanol P=2625.2 Torr; 0.166667 h; Ambient temperature;
参考文献
Ife, Robert J.; Brown, Thomas H.; Blurton, Peter; Keeling, David J.; Leach, Colin A.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 14 p. 2763 - 2773
反应条件
1: 3.4 g / KMnO4 / H2O / 2 h / 100 °C 2: 95percent hydrazine hydrate / Raney nickel / ethanol / 1 h / Heating View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 22, # 4 p. 435 - 438
Khimiya Prirodnykh Soedinenii, , vol. 22, # 4 p. 465 - 469
反应条件
hydrogenchloride in water 1 h; Heating;
参考文献
Nagasaka, Tatsuo; Koseki, Yuji
Journal of Organic Chemistry, 1998 , vol. 63, # 20 p. 6797 - 6801
反应条件
1: NaH / tetrahydrofuran; dimethylformamide 2: KMnO4, aq. NaOH 3: H2 / Pd-C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 29, p. 2003 - 2021
反应条件
hydrogenchloride Heating;
参考文献
Macdonald, Simon J. F.; McKenzie, Thomas C.; Hassen, Wesley D.
Journal of the Chemical Society, Chemical Communications, 1987 , # 20 p. 1528 - 1530
反应条件
1: 98 percent / aq. Na2CO3 / CH2Cl2 / Ambient temperature 2: 1.) nBuLi / 1.) THF, r.t.; 2.) r.t. 3: 87 percent / 25percent HCl / Heating View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 20 p. 1528 - 1530
反应条件
1: (nitration) 2: NaH / tetrahydrofuran; dimethylformamide 3: KMnO4, aq. NaOH 4: H2 / Pd-C View Scheme
参考文献
Australian Journal of Chemistry, , vol. 29, p. 2003 - 2021
反应条件
sodium hydroxide; dihydrogen peroxide
参考文献
Ramesh, M.; Shanmugam, P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 602 - 604
反应条件
1: 1.) nBuLi / 1.) THF, r.t.; 2.) r.t. 2: 87 percent / 25percent HCl / Heating View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 20 p. 1528 - 1530
反应条件
hydrogenchloride; sodium hydroxide 1.) 100 gradC, 20 min 2.) methanol, reflux, 0.5 h.; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 27, # 50 p. 6111 - 6114