4,5-二甲基-1,2-苯二胺合成路线

参考文献

Renhowe, Paul A.; Pecchi, Sabina; Shafer, Cynthia M.; Machajewski, Timothy D.; Jazan, Elisa M.; Taylor, Clarke; Antonios-McCrea, William; McBride, Christopher M.; Frazier, Kelly; Wiesmann, Marion; Lapointe, Gena R.; Feucht, Paul H.; Warne, Robert L.; Heise, Carla C.; Menezes, Daniel; Aardalen, Kimberly; Ye, Helen; He, Molly; Le, Vincent; Vora, Jayesh; Jansen, Johanna M.; Wernette-Hammond, Mary Ellen; Harris, Alex L.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 2 p. 278 - 292

3171-45-74,5-二甲基-1,2-苯二胺

2148-86-9

参考文献

Rida, Samia M.; Soliman, Farid S. G.; Badawey, El-Sayed A. M.; El-Ghazzawi, E.; Kader, O.; Kappe, Thomas
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1087 - 1093

3171-45-74,5-二甲基-1,2-苯二胺+

31541-36-3

59-48-32-吲哚酮+

71897-07-96,7-二甲基-2-苯基喹噁啉

参考文献

Alizadeh, Abdolali; Mokhtari, Javad
Helvetica Chimica Acta, 2013 , vol. 96, # 1 p. 124 - 129

144-62-7草酸+

3171-45-74,5-二甲基-1,2-苯二胺

2474-50-21,4-二氢-6,7-二甲基-2,3-喹喔啉二酮

参考文献

Liu, Jing-Horng; Wu, An-Tai; Huang, Ming-Hwei; Wu, Chein-Wei; Chung, Wen-Sheng
Journal of Organic Chemistry, 2000 , vol. 65, # 11 p. 3395 - 3403

7732-18-5水+

3171-45-74,5-二甲基-1,2-苯二胺

2474-50-21,4-二氢-6,7-二甲基-2,3-喹喔啉二酮

参考文献

State of Oregon, acting by and through the Oregon State Board of Higher Education, acting for and on behalf of the Oregon Health Sciences University and the University of Oregon, Eugene Oregon; Acea Pharmaceuticals, Inc.; The Regents of the University of California
Patent: US5631373 A1, 1997 ;

3171-45-74,5-二甲基-1,2-苯二胺+

95-92-1草酸二乙酯

2474-50-21,4-二氢-6,7-二甲基-2,3-喹喔啉二酮

参考文献

Bhat, Ajita; Chang, Hui-Min; Wallace, Lane J.; Weinstein, David M.; Shams, Gamal; Garris, Cynthia C.; Hill, Ronald A.
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 3 p. 271 - 282

127-17-3丙酮酸+

3171-45-74,5-二甲基-1,2-苯二胺

28082-86-2

参考文献

Mahesh, Radhakrishnan; Dhar, Arghya Kusum; Sasank T.v.n.v., Tara; Thirunavukkarasu, Sappanimuthu; Devadoss, Thangaraj
Chinese Chemical Letters, 2011 , vol. 22, # 4 p. 389 - 392

617-35-6丙酮酸乙酯+

3171-45-74,5-二甲基-1,2-苯二胺

28082-86-2

参考文献

Nunez-Rico, Jose Luis; Vidal-Ferran, Anton
Organic Letters, 2013 , vol. 15, # 8 p. 2066 - 2069

6000-59-5乙醛酸水合物+

3171-45-74,5-二甲基-1,2-苯二胺

28082-82-82-羟基-6,7-二甲基喹喔啉

参考文献

University of California; Yissum Research Development Company of the Hebrew University of Jerusalem; Biosignal LTD; Sugen, Inc.; Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V.
Patent: US6331555 B1, 2001 ;
US 6331555 B1

924-44-7乙醛酸乙酯+

3171-45-74,5-二甲基-1,2-苯二胺

28082-82-82-羟基-6,7-二甲基喹喔啉

参考文献

McAtee, John J.; Dodson, Jason W.; Dowdell, Sarah E.; Girard, Gerald R.; Goodman, Krista B.; Hilfiker, Mark A.; Sehon, Clark A.; Sha, Deyou; Wang, Gren Z.; Wang, Ning; Viet, Andrew Q.; Zhang, Daohua; Aiyar, Nambi V.; Behm, David J.; Carballo, Luz H.; Evans, Christopher A.; Fries, Harvey E.; Nagilla, Rakesh; Roethke, Theresa J.; Xu, Xiaoping; Yuan, Catherine C.K.; Douglas, Stephen A.; Neeb, Michael J.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 12 p. 3500 - 3503